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This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
medicines for blood pressure like diltiazem, nifedipine, verapamil
taking any other medicines
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What if I miss a dose?
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EFAVIRENZ is an antiretroviral drug. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.
This medicine may also interact with the following medications:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
Side effects that you should report to your doctor or health care professional as soon as possible:
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Take this medicine by mouth with a glass of water. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. Do not take with food. Take your dose at bedtime. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
history of depression or other mental illness
rifampin
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allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
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medicines for depression, anxiety, or psychotic disturbances
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Avoid alcohol and mood altering (street) drugs while taking this medicine because they can make these side effects worse.
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This medicine may also interact with the following medications:
medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine
medicines for cholesterol like simvastatin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dizziness
upset stomach, vomiting
 
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You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Avoid alcohol and mood altering (street) drugs while taking this medicine because they can make these side effects worse.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 3 years old for selected conditions, precautions do apply.
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