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Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, and herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.
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You may experience an increase in the number of gouty attacks for several weeks to months after starting this medicine while the body rids itself of excess uric acid. Allopurinol is not a pain reliever. To relieve pain, continue to take your prescribed medicines for gouty attacks (e.g., colchicine, ibuprofen, indomethacin) as directed by your doctor.
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Take this medication by mouth usually once daily after a meal to reduce stomach upset, or as directed by your doctor. It is best to drink a full glass of water with each dose and at least another 8 glasses (8 oz. each) a day while taking this drug in order to prevent kidney stones from forming. If you are on restricted fluid intake, consult your doctor for further instructions. Your doctor may also instruct you on how to decrease acidity in your urine (e.g., avoid large amounts of ascorbic acid or Vitamin C). Dosage is based on your medical condition and response to therapy. Use this medication regularly to get the most benefit from it. Remember to take it at the same time each day. For the treatment of gout, it may take up to several weeks for this medicine to have an effect.
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Side effects that you should report to your prescriber or health care professional as soon as possible:
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