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If you take methotrexate for rheumatoid arthritis or psoriasis, the dose is given only once a week. Do not take more frequently.
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
Side effects that you should report to your doctor or health care professional as soon as possible:
aspirin and aspirin-like medicines including bismuth subsalicylate (Pepto-Bismol)
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Take this medicine by mouth. Swallow it with a full glass of water. Do not take your medicine more often than directed. Finish the full course prescribed by your doctor or health care professional. Do not stop taking except on your doctor's advice.
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How should I use this medicine?
METHOTREXATE SODIUM is a chemotherapy drug. This medicine affects cells that are rapidly growing, such as cancer cells and cells in your mouth and stomach. It is used for leukemias, lymphomas, breast cancer, lung cancer, head and neck cancers, and other cancers. This medicine also works on the immune system and is commonly used to treat psoriasis and rheumatoid arthritis. If used for arthritis or psoriasis, the drug is only given once a week.
This list may not describe all possible side effects.
aspirin and aspirin-like medicines including bismuth subsalicylate (Pepto-Bismol)
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If you take methotrexate for rheumatoid arthritis or psoriasis, the dose is given only once a week. Do not take more frequently.
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What may interact with this medicine?
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METHOTREXATE SODIUM is a chemotherapy drug. This medicine affects cells that are rapidly growing, such as cancer cells and cells in your mouth and stomach. It is used for leukemias, lymphomas, breast cancer, lung cancer, head and neck cancers, and other cancers. This medicine also works on the immune system and is commonly used to treat psoriasis and rheumatoid arthritis. If used for arthritis or psoriasis, the drug is only given once a week.
Keep out of the reach of children.
antibiotics and other medicines for infections
vomiting
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
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rheumatrex drug This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
To protect your kidneys, drink water or other fluids as directed while you are taking this medicine.
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Keep out of the reach of children.
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
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This medicine may increase your risk of getting an infection. Stay away from people who are sick.
skin rash, hives, or itching
Side effects that you should report to your doctor or health care professional as soon as possible:
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
loss of appetite
What if I miss a dose?
What side effects may I notice from this medicine?
If you miss a dose, talk with your doctor or health care professional. Do not take double or extra doses. If you vomit after taking a dose, call your doctor or health care professional for advice.
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bleeding or blood disorders
pregnant or trying to get pregnant
Visit your doctor or health care professional for checks on your progress. You will need to have regular blood checks. You will also need a chest X-ray before starting the medicine.
breast-feeding
This medicine may increase your risk of getting an infection. Stay away from people who are sick.
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Both men and women must use effective birth control. Use 2 reliable forms of birth control together. Do not become pregnant while taking this medicine. Women should continue to use birth control until after their first normal menstrual cycle after stopping the medicine. Call your doctor right away if you think you or your partner might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine. Men should continue to use birth control for at least 3 months after stopping the medicine.
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